Title of article :
Surface plasmon resonance in monitoring of complement activation on biomaterials
Author/Authors :
Arima، نويسنده , , Yusuke and Toda، نويسنده , , Mitsuaki and Iwata، نويسنده , , Hiroo، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2011
Pages :
12
From page :
988
To page :
999
Abstract :
When artificial materials come into contact with blood, various biological responses are induced. For successful development of biomaterials used in biomedical devices that will be exposed to blood, understanding and control of these interactions are essential. Surface plasmon resonance (SPR) spectroscopy is one of the surface-sensitive optical methods to monitor biological interactions. SPR enables real-time and in situ analysis of interfacial events associated with biomaterials research. In this review, we describe an SPR biosensor and its application to monitor complement activation onto biomaterials surface. We also discuss the effect of surface properties of the material on complement activation.
Keywords :
surface plasmon resonance , complement activation , Self-assembled monolayer , Polymer Coating , The classical pathway , Nonspecific protein adsorption , The alternative pathway
Journal title :
Advanced Drug Delivery Reviews
Serial Year :
2011
Journal title :
Advanced Drug Delivery Reviews
Record number :
1763198
Link To Document :
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