Title of article :
Carbon nanotubes for delivery of small molecule drugs
Author/Authors :
Wong، نويسنده , , Bin Sheng and Yoong، نويسنده , , Sia Lee and Jagusiak، نويسنده , , Anna and Panczyk، نويسنده , , Tomasz and Ho، نويسنده , , Han Kiat and Ang، نويسنده , , Wee Han and Pastorin، نويسنده , , Giorgia، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Pages :
52
From page :
1964
To page :
2015
Abstract :
In the realm of drug delivery, carbon nanotubes (CNTs) have gained tremendous attention as promising nanocarriers, owing to their distinct characteristics, such as high surface area, enhanced cellular uptake and the possibility to be easily conjugated with many therapeutics, including both small molecules and biologics, displaying superior efficacy, enhanced specificity and diminished side effects. While most CNT-based drug delivery system (DDS) had been engineered to combat cancers, there are also emerging reports that employ CNTs as either the main carrier or adjunct material for the delivery of various non-anticancer drugs. s review, the delivery of small molecule drugs is expounded, with special attention paid to the current progress of in vitro and in vivo research involving CNT-based DDSs, before finally concluding with some consideration on inevitable complications that hamper successful disease intervention with CNTs.
Keywords :
Carbon nanotubes , Non-anticancer drugs , DRUG DELIVERY , Small molecule drugs , anticancer drugs
Journal title :
Advanced Drug Delivery Reviews
Serial Year :
2013
Journal title :
Advanced Drug Delivery Reviews
Record number :
1763902
Link To Document :
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