Title of article :
Promise and problems in relating cellular senescence in vitro to aging in vivo
Author/Authors :
Rubin، نويسنده , , Harry، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
According to the ‘Hayflick limit’, human fetal fibroblasts have a uniform, limited replicative lifespan of about 50 population doublings in cell culture. This concept was extrapolated to diverse cells in the body. It seemed to decrease with the age of the
Keywords :
Telomerases , Fibroblasts in vitro , Hayflickיs limit , In vitro aging , Lipofuscin production in vitro , telomeres , In vivo aging
Journal title :
Archives of Gerontology and Geriatrics
Journal title :
Archives of Gerontology and Geriatrics
