Author/Authors :
Li، نويسنده , , Hongbin and Rief، نويسنده , , Matthias and Oesterhelt، نويسنده , , Filipp and Gaub، نويسنده , , Hermann E and Zhang، نويسنده , , Xi-hai Shen، نويسنده , , Jiacong، نويسنده ,
Abstract :
AFM-based single-molecule force spectroscopy was employed to measure the nanomechanical properties of 1,4-linked polysaccharides. Single-molecule force spectroscopy clearly reflected the difference in the mechanical properties of α-(1,4)- and β-(1,4)-linked polysaccharides. A force-induced chair–twist boat conformational transition in α-(1,4)-linked polysaccharides was discovered. This chair–twist boat conformational transition is a nanomechanical fingerprint of α-(1,4)-linked polysaccharides.
