Author/Authors :
Etchegoin، نويسنده , , P and Maher، نويسنده , , R.C and Cohen، نويسنده , , L.F and Hartigan، نويسنده , , H and Brown، نويسنده , , R.J.C. and Milton، نويسنده , , M.J.T and Gallop، نويسنده , , J.C، نويسنده ,
Abstract :
We show the possibility of chemical tracing in solution down to a concentration of a fraction of an atto mol (10−18) by means of non-resonant surface enhanced Raman scattering (SERS). The experiments are demonstrated with rhodamine 6G dissolved in water. Based on our results here, we propose a technique for counting a small number of SERS active molecules in micro-droplets of liquid. It is argued that, by choosing the appropriate SERS enhancement condition, the technique could be used and implemented as a routine analytical method with unprecedented detection capabilities for the monitoring and tracing of important families of biomolecules.
