Sorption studies of metal ions on napthol blue–black modified Amberlite IR-400 anion exchange resin: Separation and determination of metal ion contents of pharmaceutical preparation

Anion exchange resin Amberlite IR-400 has been modified with napthol blue–black. Effect of concentration, time, pH and temperature on the sorption of dye has been studied. The uptake sequence of various metal ions in a number of solvents has been determined. On the basis of distribution coefficients (Kd) in a number of solvent systems, some important binary separations of metal ions of analytical interest have been exploited. The practical applicability of the modified material has been demonstrated in the analysis of synthetic and commercially available antacid and antioxidant formulations namely digene and I-Vit.