Title of article :
Downregulation of Selected Cytokines in Amebiasis
Author/Authors :
Bekker-Mendez، نويسنده , , Vilma Carolina and Pérez-Castillo، نويسنده , , Viola Leticia and Rico-Rosillo، نويسنده , , Marيa Guadalupe and Pérez-Rodrيguez، نويسنده , , Martha and Arellano-Blanco، نويسنده , , Jorge and Kretschmer-Schmid، نويسنده , , Roberto Rodolfo and Talamلs-Rohana، نويسنده , , Patricia، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A 220-kDa E. histolytica lectin is capable of downregulating some inflammatory cytokines (IL-5, IL-6, INF-γ and TNF-α) and thus of inducing an overall anti-inflammatory Th-phenotype in leucocytes of selected, perhaps constitutionally predisposed, individuals irrespective of their HLA-DR3 profile (i.e., in this study patients long recovered from amebic abscess of the liver). This probably inhibited cytokine response pattern could increase the risk for developing amebic abscess of the liver in the course of invasive intestinal amebiasis.
Keywords :
E. histolytica , cytokines , Lectins , inflammation
Journal title :
Archives of Medical Research
Journal title :
Archives of Medical Research