Title of article
Anticancer and antioxidant activity of synthetic chalcones and related compounds
Author/Authors
Anto، نويسنده , , Ruby John and Sukumaran، نويسنده , , K. and Kuttan، نويسنده , , Girija and Rao، نويسنده , , M.N.A. and Subbaraju، نويسنده , , V. and Kuttan، نويسنده , , Ramadasan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
5
From page
33
To page
37
Abstract
Nineteen synthetic chalcones and ten structurally related compounds were investigated for their cytotoxic, tumour reducing and antioxidant activities. Methyl and hydroxy substituted chalcones were found to be cytotoxic in vitro whereas only hydroxy substituted chalcones could reduce ascites tumour in animals. Although most of the compounds analysed showed antioxidant activity, hydroxy and methyl substituted compounds were found to be the most potent antioxidants.
Keywords
Synthetic chalcones , antitumour activity , antioxidant activity
Journal title
Cancer Letters
Serial Year
1995
Journal title
Cancer Letters
Record number
1797038
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