Title of article :
8-Oxo-2′-deoxyguanosine level in lymphocytes DNA of cancer patients undergoing radiotherapy
Author/Authors :
Bialkowski، نويسنده , , Karol and Kowara، نويسنده , , Renata and Windorbska، نويسنده , , Wieslawa and Olinski، نويسنده , , Ryszard، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
We analyzed the level of 8-oxo-2′-deoxyguanosine in lymphocytes DNA of cancer patients undergoing radiotherapy. The results of this work indicate that exposure of cancer patients to therapeutic doses of ionizing radiation causes significant increase of the amount of 8-oxo-dG in DNA isolated from their lymphocytes.
Keywords :
8-oxo-2?-deoxyguanosine , 8-hydroxydeoxyguanosine , DNA damage , CANCER , radiotherapy , Nucleobase modification
Journal title :
Cancer Letters
Journal title :
Cancer Letters