Author/Authors :
Koyama، نويسنده , , Junko and Tagahara، نويسنده , , Kiyoshi and Osakai، نويسنده , , Toshiyuki and Tsujino، نويسنده , , Yoshio and Tsurumi، نويسنده , , Seiji and Nishino، نويسنده , , Hoyoku and Tokuda، نويسنده , , Harukuni، نويسنده ,
Abstract :
The redox potentials have been determined for nine anthraquinones in phosphate buffer at pH 7.2 by means of cyclic voltammetry. A definite correlation has been found between the redox potentials and the inhibitory effects of the anthraquinones on the EBV-EA activation. It has further been shown that the correlation can be made better by introducing an electronic property, i.e. the atomic charge at O12 as an additional parameter.
Keywords :
Anti-tumor promoting effect , Epstein-Barr virus activation , Anthraquinones , Standard redox potential , Cyclic voltammetry , atomic charge
