Title of article
Inhibitory effect of soybean hypocotyls on Epstein–Barr virus early antigen induction and skin tumor promotion
Author/Authors
Zaizen، نويسنده , , Yukihiro and Tokuda، نويسنده , , Harukuni and Nishino، نويسنده , , Hoyoku and Takeshita، نويسنده , , Masazumi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
5
From page
53
To page
57
Abstract
The in vitro anti-tumor promoting effect of hypocotyls from fresh soybeans was evaluated. The dimethyl sulfoxide extracts of hypocotyls showed a stronger inhibitory effect than that of soybeans on Epstein–Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol-13-acetate. Daidzin, an isoflavone with the highest content of hypocotyls, was also inhibitory. An in vivo evaluation of anti-tumor promoting activity of hypocotyls against the skin of mice also revealed a significant inhibitory effect on tumor formation.
Keywords
Soybean hypocotyl , Anti-tumor promoting effect , Epstein–Barr virus early antigen , Mouse skin tumor , isoflavonoid
Journal title
Cancer Letters
Serial Year
1997
Journal title
Cancer Letters
Record number
1799116
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