Author/Authors :
Battisti، نويسنده , , Carla and Formichi، نويسنده , , Patrizia and Tripodi، نويسنده , , Sergio Antonia and Vindigni، نويسنده , , Carla and Roviello، نويسنده , , Francesco and Federico، نويسنده , , Antonia، نويسنده ,
Abstract :
Alpha-tocopherol has been reported to play an important role against oxidative damage and in the inhibition of cell transforming and mutagenesis. We analysed vitamin E serum levels in 51 cases of patients affected by gastric cancer at different stages of the disease, and in 49 age-matched controls. All patients had normal values of alpha-tocopherol. However, when patients have been grouped according to histotype of gastric lesions, a significant vitamin E increase has been found in diffuse gastric cancer histotype compared to the intestinal histotype. Our results suggest that a correlation between vitamin E serum levels and gastric cancer histotype should be considered.
