Title of article
Detection and expression of Epstein-Barr Virus (EBV) DNA in tissues from penile tumors in Brazil
Author/Authors
Alves، نويسنده , , Gilda and Menezes Trindade Macrini، نويسنده , , Camila and de Souza Nascimento، نويسنده , , Patrيcia and Carlos Morais، نويسنده , , José and Augusto Ornellas، نويسنده , , Antonio، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
79
To page
82
Abstract
Epstein-Barr Virus (EBV) is prevalent in all human populations and high titers of antibody correlate with specific malignancies such as Burkittʹs lymphoma, nasopharyngeal carcinoma, and Hodgkinʹs disease. Our study detected EBV DNA in 20 of 21 penile tumor samples using PCR reaction. Expression of EBV protein LMP-1 was identified in tumor cells from two EBV PCR-positive tumors. Our findings indicate that EBV can be implicated in rising and/or progression of penile tumors independently of the histological type.
Keywords
Penile tumor , EBV , LMP-1
Journal title
Cancer Letters
Serial Year
2004
Journal title
Cancer Letters
Record number
1807075
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