Author/Authors :
Koyama، نويسنده , , Junko and Morita، نويسنده , , Izumi and Kobayashi، نويسنده , , Norihiro and Konoshima، نويسنده , , Takao and Takasaki، نويسنده , , Midori and Osakai، نويسنده , , Toshiyuki and Tokuda، نويسنده , , Harukuni، نويسنده ,
Abstract :
The oxidation potentials of fifteen flavonoids in phosphate buffer at pH 7.2 were determined by cyclic voltammetry. A good correlation was found between these oxidation potentials and the ability of flavonoids to inhibit Epstein–Barr virus early antigen (EBV-EA) activation. Furthermore, multiple regression analysis revealed that the solvent-accessible surface area (SASA) was a useful parameter for estimating the inhibitory effects of flavonoids on EBV-EA activation.
Keywords :
Oxidation potential , Flavonoid , Cyclic voltammetry , Epstein–Barr virus early antigen
