Title of article
Clinicopathological significance of peritumoral lymphatic vessel density in gastric carcinoma
Author/Authors
Gao، نويسنده , , Peng and Zhou، نويسنده , , Geng-Yin and Zhang، نويسنده , , Qing-Hui and Xiang، نويسنده , , Lei and Zhang، نويسنده , , Shun-Li and Li، نويسنده , , Chao and Sun، نويسنده , , Yan-Lin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
8
From page
223
To page
230
Abstract
Lymphangiogenesis has recently been considered important for spread of malignant tumors. In the present study, lymphatic vessel density (LVD) including peritumoral LVD (P-LVD) and intratumoral LVD (I-LVD) was determined, respectively, by immunohistochemical staining with the antibody to LYVE-1 in 63 cases of early gastric carcinoma and 105 cases of advanced gastric carcinoma. The aim of the study is to investigate whether or not increased LVD could be a risk factor for nodal metastasis and survival. We conclude that increased P-LVD, but not I-LVD, could serve as an independent risk factor for nodal metastasis, recurrence and overall survival in gastric carcinoma.
Keywords
Gastric Carcinoma , Lymphatic vessel density (LVD) , LYVE-1 , Prognosis , Lymphangiogenesis
Journal title
Cancer Letters
Serial Year
2008
Journal title
Cancer Letters
Record number
1811901
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