• Title of article

    Effects of dietary broccoli on human drug metabolising activity

  • Author/Authors

    Kall، نويسنده , , Morten A. and Vang، نويسنده , , Ole Petter Clausen، نويسنده , , Jّrgen، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    2
  • From page
    169
  • To page
    170
  • Abstract
    Eighteen volunteers received 500 g fresh broccoli every day for 12 days after a 6-day period of standard diet. The activity of CYP1A2, CYP2E1 and the estrone 2 and 16α-hydroxylation were determined prior to and after the broccoli diet. The average activity of CYP1A2 and the average 2/16α-hydroxyestrone ratio were increased 19% (P < 0.0005) and 29.5% (P < 0.05), respectively; however, no effects were observed on the CYP2E1 activity.
  • Keywords
    broccoli , Metabolising enzymes , CYP1A2 , CYP2E1 , indole-3-carbinol , glutathione S-transferase
  • Journal title
    Cancer Letters
  • Serial Year
    1997
  • Journal title
    Cancer Letters
  • Record number

    1815588