Author/Authors :
Shakouie، Sahar نويسنده , , Eskandarinezhad، Mahsa نويسنده Department of Endodontics, Dental School, Tabriz University of Medical Sciences, Tabriz, Iran , , Ghasemi، Negin نويسنده Department of Endodontics, Dental School, Tabriz University of Medical Sciences, Tabriz, Iran , , Salem Milani، Amin نويسنده Dental and periodontal disease research center, Dental School, Tabriz University of Medical Sciences, Tabriz, Iran , , Samiei، Mohammad نويسنده Department of Endodontics, Dental School, Tabriz University of Medical Sciences, Tabriz ,Iran , , Golizadeh، Sara نويسنده Private Practice, Tehran, Iran ,
Abstract :
Introduction: The antimicrobial efficacy of root canal irrigant plays an important role in
increasing the success of root canal treatment (RCT). The aim of the present experimental study
was to compare the antimicrobial activity of Triphala (a plant-derived solution) with 0.5, 1, 2.5 and
5% concentrations of sodium hypochlorite (NaOCl), against Enterococcus faecalis (E. faecalis).
Methods and Materials: Two hundred plates of cultured E. faecalis, were divided into 5
experimental groups (n=38) and two positive and negative control groups. The antimicrobial
activity of the test solutions was determined by measuring the zone of inhibition in the culture
media. The mean diameter of inhibited zones between the study groups was compared using the
Kruskal-Wallis test and the Mann-Whitney U test was used for the two-by-two comparison of the
groups with the level of significance set at 0.05. Results: The Kruskal-Wallis test showed significant
differences between the study groups (P < 0.05). According to the Mann-Whitney U test the mean
diameter of inhibition zones in Triphala group was significantly higher compared to 0.5 and 1%
NaOCl (P < 0.05). Conclusion: In this study, Triphala exhibited better antimicrobial activity against
E. faecalis compared to 0.5 and 1% NaOCl (P < 0.05).
