Title of article
Detection of cerebroside sulfotransferase mRNA in human gastric mucosa and adenocarcinoma
Author/Authors
Kobayashi، نويسنده , , Takahiko and Honke، نويسنده , , Koichi and Tsunematsu، نويسنده , , Izumi and Kagaya، نويسنده , , Hidetoshi and Nishikawa، نويسنده , , Shuji and Hokari، نويسنده , , Kaku and Kato، نويسنده , , Mototsugu and Takeda، نويسنده , , Hiroshi and Sugiyama، نويسنده , , Toshiro and Higuchi، نويسنده , , Akifumi and Asaka، نويسنده , , Masahiro، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
7
From page
45
To page
51
Abstract
Sulfatide is a major acidic glycolipid in human gastric mucosa, and its sulfation is catalyzed by cerebroside sulfotransferase (CST). To investigate the expression of the CST gene in human gastric cancer, a reverse transcription PCR method was developed with the use of endoscopic bioptic specimens. By this method, we examined the CST mRNA expression in 11 cases of gastric cancer, and in all the cases we detected various levels of the expression both in cancer tissues and in uninvolved adjacent tissues. The present assay method was suggested to be useful in the detection of CST mRNA from a limited amount of bioptic samples.
Keywords
Sulfatide , Gastric cancer , sulfotransferase , Glycolipid
Journal title
Cancer Letters
Serial Year
1999
Journal title
Cancer Letters
Record number
1816728
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