Title of article
Changes in serum diamine oxidase activity during chemotherapy in patients with hematological malignancies
Author/Authors
Tsujikawa، نويسنده , , Tomoyuki and Uda، نويسنده , , Katsuhiro and Ihara، نويسنده , , Takashi and Inoue، نويسنده , , Tetsuya and Andoh، نويسنده , , Akira and Fujiyama، نويسنده , , Yoshihide and Bamba، نويسنده , , Tadao، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
195
To page
198
Abstract
Serum diamine oxidase (DAO) activity is very low, but is considered to reflect quantitative changes in small intestinal mass. Therefore, we measured DAO activity during chemotherapy in patients with hematological malignancies in order to evaluate mucosal injury. DAO activity decreased from 1–3 weeks after chemotherapy but returned to initial levels after 4 weeks. As the dosage of anti-cancer drugs increased, DAO activity decreased more, but its activity was not related to other parameters. These findings suggest that serum DAO could be used as an indicator of mucosal injury during chemotherapy.
Keywords
diamine oxidase , chemotherapy , Mucosal injury
Journal title
Cancer Letters
Serial Year
1999
Journal title
Cancer Letters
Record number
1817046
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