Author/Authors :
Yule، نويسنده , , S.M and Bown، نويسنده , , N and Malcolm، نويسنده , , A.J. and Reid، نويسنده , , M.M and Pearson، نويسنده , , A.D.J، نويسنده ,
Abstract :
We report a child with a progressive “solid alveolar rhabdomyosarcoma” in whom analysis of tumor cells revealed a t(2;13) translocation characteristic of the classical alveolar subtype. Both subtypes of alveolar rhabdomyosarcoma are associated with a poor response to treatment and the occurrence of this translocation in both is suggestive of a common biologic origin.