Author/Authors :
Scaravaglio، نويسنده , , Patrizia and Saglio، نويسنده , , Giuseppe and Geuna، نويسنده , , Massimo and Palestro، نويسنده , , Giorgio and Guglielmelli، نويسنده , , Tommasina and Rege-Cambrin، نويسنده , , Giovanna، نويسنده ,
Abstract :
In a case of immunoblastic lymphoma we observed the presence of either a deletion of the long arm of chromosome 6 or of an isochromosome, i(6p), which occurred alternatively in metaphase cells. This suggest a selective pressure for loss of heterozygosity of genes located on 6q and is in accordance with the hypothesis that one or more tumor suppressor genes might be located on the long arm chromosome 6.
