Author/Authors :
van Echten، نويسنده , , Jannie and van den Berg، نويسنده , , Eva and van Baarlen، نويسنده , , Joop and van Noort، نويسنده , , Gerard and Vermey، نويسنده , , Albert and Dam، نويسنده , , Anke and Molenaar، نويسنده , , Willemina M. Molenaar، نويسنده ,
Abstract :
A cytogenetic study of two cases of alveolar soft part sarcoma showed near-diploid karyotypes with multiple chromosomal rearrangements. An abnormality of the long arm of chromosome 17, involving band q25, is present in both cases and in 2 of 4 cases in the literature. This recurrent structural abnormality probably plays an important role in the histogenesis of this unusual neoplasm and therefore is important for further molecular investigation.