Author/Authors :
Casalone، نويسنده , , R. and Minelli، نويسنده , , E. and Righi، نويسنده , , R. and Granata، نويسنده , , P. L. Meroni، نويسنده , , E. and Caruso، نويسنده , , V. and Mazzola، نويسنده , , D. and Salvadore، نويسنده , , M. and Pozzi، نويسنده , , E. Gonzalez-Bono، نويسنده , , A.V.، نويسنده ,
Abstract :
Cytogenetic analysis was performed on 23 samples from non-neoplastic ureters. Clonal chromosome abnormalities were found in eight. They were: loss of Y chromosome, as a single abnormality (five cases) or associated with trisomy 10 and 20 (one case) or with trisomy 2 (one case); and duplication of Y chromosome (one case). Different numerical and structural sporadic abnormalities were found in nine cases. Immunohistochemical analysis and direct observation using the inverted microscope showed that the cells were mainly of the fibroblastic type. FISH analysis with chromosome 7 α-satellite probes failed to detect the presence of trisomy 7 in three epithelial cases tested.
