Title of article
An unusual cytogenetic abnormality involving chromosomes 1 and 7 in a case of chronic myelomonocytic leukemia
Author/Authors
Papadhimitriou، نويسنده , , Stefanos I. and Abazis، نويسنده , , Danae and Repa، نويسنده , , Constantina and Papaconstantinou، نويسنده , , Christos and Papanastasiou، نويسنده , , Constantinos and Pangalos، نويسنده , , Constantinos and Stamatelou، نويسنده , , Marina، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
3
From page
75
To page
77
Abstract
We report a case of chronic myelomonocytic leukemia in which cytogenetic analysis revealed a 47,XY, +1, + der(7)del(7)(q32q36)ins(7;1)(q32;p36.3p22) chromosomal constitution. This abnormal karyotype, which as a whole is new to any myeloid malignancy, points to a possible pathogenetic role for the oncogenes MET and FGR on the derivative chromosome 7, and for the CSF1 and JUN genes flanking the breakpoint on chromosome 1.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1995
Journal title
Cancer Genetics and Cytogenetics
Record number
1818430
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