Author/Authors :
Iwama، نويسنده , , Hiroshi and Ohyashiki، نويسنده , , Kazuma and Ohyashiki، نويسنده , , Junko H. and Shimamoto، نويسنده , , Takashi and Fujimura، نويسنده , , Toshikatsu and Kawakubo، نويسنده , , Ken and Kuriyama، نويسنده , , Yuzuru and Kodama، نويسنده , , Atsushi and Toyama، نويسنده , , Keisuke، نويسنده ,
Abstract :
We describe the first case of acute myeloid leukemia (AML) with a Philadelphia (Ph) translocation and a near-hexaploid range chromosome number, whose leukemic cells had the major-BCR/ABL transcript. The genesis of near-hexaploid leukemic cells might be due to endoreduplication of triploid leukemic cells with the Ph, since the relapsed leukemic cells had triploid range chromosomes with double Ph chromosomes.
