A unique clonal chromosome 2 deletion in endomyometriosis

The cytogenetic analysis of a short-term culture from a so-called endomyometriosis revealed a unique clonal del(2)(p21). The embryologic origin of this uterine-like mass is controversial. The finding of a clonal chromosome aberration favors the proliferation hypothesis and suggests that endomyometriosis is a true neoplams and that a somatic mutation might be involved in the etiology of this lesion.