Author/Authors :
Bol، نويسنده , , Silvia and Wanschura، نويسنده , , Sylke and Thode، نويسنده , , Brita and Deichert، نويسنده , , Ulrich and Van de Ven، نويسنده , , Wim J.M. and Bartnitzke، نويسنده , , Sabine and Bullerdiek، نويسنده , , Jِrn، نويسنده ,
Abstract :
Cytogenetic studies of an endometrial polyp of an 82-year-old patient revealed a karyotype 46,XX,der(2)inv(2)(p25q21)ins(2;12)(p25;q13q14)t(2;12)(q21;q15),der(12)del(12)(q13q14)del(12)(q15). By fluorescence in situ hybridization (FISH) we found the chromosome 12 translocation breakpoint to be mapping within the third intron of the HMGI-C gene also harboring the breakpoints of translocations involving 12q15 seen in uterine leiomyomas, lipomas, pleomorphic adenomas, and pulmonary chondroid hamartomas.
