Development of surface-functionalized drug-eluting stent with diamond-like carbon nanocoated by using PECVD method

We attempted the surface modification of stents using functionalised functionalized DLC films in order to improve the adhesion and integrity of drug drug-eluting polymers. We doped Si for the improvement of mechanical properties of DLC films, and modified the surface of DLC films using oxygen plasma. The result of the analysis after the plasma treatment showed that oxidation of Si occurred, and that the introduction of O C–O bonding decreased as the amount of doped Si increased. We deduced that the reduction of Si concentrations from the surface of DLC films was effective for introducing OC–O bonding. The results obtained from these composition analyses were applied to drug-eluting stents and it was confirmed that the peeling of polymers did not readily occur.