Title of article
Acute myeloblastic leukemia associated with trisomy 8 and translocation 8;21 in a child with Down syndrome
Author/Authors
Yamaguchi، نويسنده , , Yukitoshi and Fujii، نويسنده , , Hideki and Kazama، نويسنده , , Hiromi and Iinuma، نويسنده , , Kazuso and Shinomiya، نويسنده , , Noriaki and Aoki، نويسنده , , Tsugutoshi Aoki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
3
From page
32
To page
34
Abstract
The present study examined an 11-year-old girl with Down syndrome who suffered from acute myeloblastic leukemia (AML) preceded by preleukemic pancytopenia. Chromosomal analysis of leukemic cells revealed a chromosome change at t(8;21) and trisomy 8 associated with constitutional trisomy 21. Treatment with antineoplastic agents led to complete remission.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1997
Journal title
Cancer Genetics and Cytogenetics
Record number
1820268
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