Author/Authors :
Yamaguchi، نويسنده , , Yukitoshi and Fujii، نويسنده , , Hideki and Kazama، نويسنده , , Hiromi and Iinuma، نويسنده , , Kazuso and Shinomiya، نويسنده , , Noriaki and Aoki، نويسنده , , Tsugutoshi Aoki، نويسنده ,
Abstract :
The present study examined an 11-year-old girl with Down syndrome who suffered from acute myeloblastic leukemia (AML) preceded by preleukemic pancytopenia. Chromosomal analysis of leukemic cells revealed a chromosome change at t(8;21) and trisomy 8 associated with constitutional trisomy 21. Treatment with antineoplastic agents led to complete remission.
