Author/Authors :
Molenaar، نويسنده , , Willemina M. and Dijkhuizen، نويسنده , , Trijnie and van Echten، نويسنده , , Jannie and Hoekstra، نويسنده , , Harald J. and van den Berg، نويسنده , , Eva، نويسنده ,
Abstract :
A 62-year-old woman presented with a solitary diffuse neurofibroma; a second recurrence showed features indicative of malignancy, but insufficient for a certain histologic diagnosis. Cytogenetic analysis revealed abnormalities previously described in malignant peripheral nerve sheath tumors and not in their benign counterparts, thus supporting the histologic suspicion of emerging malignancy.