Title of article
Enhanced expression in seminoma of human zinc finger genes located on chromosome 19
Author/Authors
Ogawa، نويسنده , , Takehiko and Poncelet، نويسنده , , Dominique A and Kinoshita، نويسنده , , Yuzo and Noce، نويسنده , , Toshiaki and Takeda، نويسنده , , Mitsumasa and Kawamoto، نويسنده , , Kanji and Udagawa، نويسنده , , Koichi and Lecocq، نويسنده , , Pierre J and Marine، نويسنده , , Jean-Christophe and Martial، نويسنده , , Joseph A and Hosaka، نويسنده , , Masahiko، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
7
From page
36
To page
42
Abstract
Six Krüppel-type zinc finger (ZF) genes were cloned from a seminoma cDNA library. One, ZFS-1, showed high sequence homology to the ZNF91 KMAB (Krüppel-associated box) ZF gene family and also the same chromosomal assignment. Interestingly, Northern blot analyses using ZFS-1 and ZNF91 revealed that multiple ZF genes on chromosome 19 were predominantly expressed in seminomas. In addition, the testis and the seminoma showed specific expression of 2.3 kb transcript. Our results suggest that ZF genes on chromosome 19 may be implicated in the development and/or growth of seminomas.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1998
Journal title
Cancer Genetics and Cytogenetics
Record number
1820849
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