Author/Authors :
Panarello، نويسنده , , Claudio and Rosanda، نويسنده , , Cristina and Morerio، نويسنده , , Cristina and Russo، نويسنده , , Ivana and Dallorso، نويسنده , , Sandro and Gambini، نويسنده , , Claudio and Ricco، نويسنده , , Angela Serena and Storlazzi، نويسنده , , Tiziana and Archidiacono، نويسنده , , Nicoletta and Rocchi، نويسنده , , Mariano، نويسنده ,
Abstract :
Lipoblastoma is a rare benign adipose tumor which, in all of the cases so far described, presents an involvement of chromosome 8 in the region 8q11-13. We hereby report the results of the second case of lipoblastoma studied by fluorescence in situ hybridization (FISH), in a 13-month-old boy. An abnormal karyotype 46,XY,t(7;8)(q31;q13) was found in 90% of the metaphases examined, in agreement with the previously reported observations. We suggest the region 8q11-13 may contain a relevant locus for lipoblastoma origin.
