Title of article
Translocation (3;16)(q27;p11) in a Patient with Diffuse Large B-Cell Lymphoma Associated with the BCL-6 Gene Rearrangement
Author/Authors
Takako and Ichinohasama، نويسنده , , Ryo and Miura، نويسنده , , Ikuo and Shishido، نويسنده , , Tomoaki and Matsumoto، نويسنده , , Keisuke and Shimizu، نويسنده , , Yoshinaka and Miki، نويسنده , , Tohru and DeCoteau، نويسنده , , John F and Kadin، نويسنده , , Marshall E and Ooya، نويسنده , , Kiyoshi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
7
From page
133
To page
139
Abstract
A patient with B-cell lineage diffuse large-cell lymphoma carrying the t(3;16)(q27;p11) and BCL-6 rearrangement is described. Cytogenetic studies showed 46,XY,t(3;16)(q27;p11.2)[11]/46,idem,add(18)(q21)[7]/46,XY[2]. The chromosomal translocation involving the 3q27 locus was associated with the BCL-6 gene rearrangement identified by Southern blot analysis. This case involved systemic lymph nodes, as large as 3 cm in diameter, bilaterally in neck, axilla, and inguinal regions. The patient obtained complete remission with chemotherapy.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1998
Journal title
Cancer Genetics and Cytogenetics
Record number
1821196
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