Author/Authors :
Sainati، نويسنده , , Laura and Leszl، نويسنده , , Anna and Stella، نويسنده , , Mario and Montaldi، نويسنده , , Anna and Perilongo، نويسنده , , Giorgio and Rugge، نويسنده , , Massimo and Bolcato، نويسنده , , Sonia and Iolascon، نويسنده , , Achille and Basso، نويسنده , , Giuseppe، نويسنده ,
Abstract :
Hepatoblastoma is a rare pediatric malignant tumor of the liver. Previous cytogenetic reports are sporadic. We karyotyped nine consecutive hepatoblastomas from the Italian centers participating in a multicentric study on hepatic tumors (SIOPEL 1). Six cases showed abnormal karyotypes. The most common abnormalities were trisomies of chromosomes 2 and 20. Four cases showed abnormalities of chromosome 1. On the basis of findings, we speculate the possibility of a cytogenetic evolutive pattern of hepatoblastomas.
