Author/Authors :
Bernasconi، نويسنده , , P. and Cavigliano، نويسنده , , P.M. and Genini، نويسنده , , E. and Castagnola، نويسنده , , C. and Malcovati، نويسنده , , L. and Calatroni، نويسنده , , S. and Caresana، نويسنده , , M. and Boni، نويسنده , , M. and Alessandrino، نويسنده , , E.P. and Astori، نويسنده , , C. and Corso، نويسنده , , A. and Bernasconi، نويسنده , , C.، نويسنده ,
Abstract :
Complete or partial monosomy for the long arms of chromosomes 5 or 7 or both is frequently observed in therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia. Sporadic cases have been reported in which partial monosomy is due to unbalanced translocations. The patient described herein carries one such rearrangement, 46,XY,t(1;2)(q32;p23),del(5)(q13),der(7)(5qter → 5q22::7p15→7q21:),del(12)(p12), resulting in partial monosomy for the long arms of chromosomes 5 and 7 and in partial monosomy for the short arm of chromosome 7.
