Author/Authors :
Christian Herens، نويسنده , , Christian and Hermanne، نويسنده , , Jean-Philippe and Tassin، نويسنده , , Francoise and Fassotte، نويسنده , , Marie France and Thiry، نويسنده , , Albert and Jamar، نويسنده , , Mauricette and Schaaf-Lafontaine، نويسنده , , Nicole and Fillet، نويسنده , , Georges and Koulischer، نويسنده , , Lucien، نويسنده ,
Abstract :
Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.
