Solitary Fibrous Tumor of the Pleura: A Cytogenetic Study

A solitary fibrous tumor of the pleura was studied. Its karyotype was 46,XY,t(6;17)(p11.2;q23),ins(9;12)(q22;q15q24.1),inv(16)(p13.1q24). The rearrangement of 12q13–15 was also described in a subset of hemangiopericytomas of soft tissue and meninges. Because both types of tumors are morphologically and immunophenotypically quite similar, and because some of them share rearrangement of 12q13–15, the possibility of their histogenetical relatedness should be considered.