Author/Authors :
Marco ، نويسنده , , Fernando and Bureo، نويسنده , , Encarnaciَn and Delgado، نويسنده , , M.Dolores and Richard، نويسنده , , Carlos and Cuadrado، نويسنده , , M.Angeles and Retortillo، نويسنده , , José A.Pérez and Recio، نويسنده , , Marina and Zubizarreta، نويسنده , , Alberto، نويسنده ,
Abstract :
Molecular rearrangements of the MLL gene at the 11q23 region have been identified in most cases of infant leukemia, regardless of the phenotype. We present a case of acute myeloid leukemia which coexpressed myeloid and lymphoid markers in a 12-month-old girl. Karyotype analysis revealed the presence of a thus far unreported translocation t(10;11)(p13;p15). Although no 11q23 abnormalities were cytogenetically detectable, an MLL gene molecular rearrangement was found.
