Author/Authors :
Sonobe، نويسنده , , Hiroshi and Iwata، نويسنده , , Jun and Komatsu، نويسنده , , Takeki and Fukushima، نويسنده , , Atsuki and Hayashi، نويسنده , , Nobutsugu and Moriki، نويسنده , , Toshiaki and Shimizu، نويسنده , , Kiichi and Ohtsuki، نويسنده , , Yuji، نويسنده ,
Abstract :
Giant cell angiofibroma, a recently proposed new clinicopathological entity, arises exclusively in the orbit in adults and histologically exhibits features intermediate between those of giant cell fibroblastoma and solitary fibrous tumor. In a typical case of giant cell angiofibroma, abnormalities of chromosome 6 with a common pattern involving 6q13 were detected together with various other chromosomal aberrations. To our knowledge, this is the first reported case of giant cell angiofibroma demonstrating chromosomal abnormalities.
