Translocation (5;9)(q22;q34) in a Case of Acute Lymphoblastic Leukemia with Multiple Bone Involvement: Effectiveness of Donor Lymphocyte Infusion for Relapse after Allogeneic Stem Cell Transplantation

A case of acute lymphoblastic leukemia with a new translocation, t(5;9)(q22;q34) is reported with special reference to the clinical features and the response to treatment. This case exhibited several unique clinical features, including expression of the myeloid antigen on the early pre-B-cell phenotype, multiple bone involvement, and favorable response to donor lymphocyte infusion despite early relapse after allogeneic hematopoietic stem cell transplantation.