Author/Authors :
Llewellyn، نويسنده , , Imogen E and Morris، نويسنده , , Christine M and Stanworth، نويسنده , , Simon P. Heaton، نويسنده , , David C and Spearing، نويسنده , , Ruth L، نويسنده ,
Abstract :
Trisomy 10 is a rare nonrandom cytogenetic abnormality found in association with acute myeloid leukemia (AML). The hematological and clinical features associated with this finding have not yet been clearly defined. A literature review revealed 13 cases of trisomy 10 in AML, some reported as a minority component of a more comprehensive AML study and therefore lacking a full description of both clinical and hematological features. We present a summary of these reports and add three new cases to the literature.