Author/Authors :
Burbano، نويسنده , , Rommel Rodr??guez and Medeiros، نويسنده , , Arnaldo and de Amorim، نويسنده , , Mar?cia Irena Medeiros and Lima، نويسنده , , Eleonidas Moura and Mello، نويسنده , , Adriano and Neto، نويسنده , , José Barbieri and Casartelli، نويسنده , , Cacilda Rosa Mitiko Kondo، نويسنده ,
Abstract :
Generally, benign breast lesions behave like innocuous and limited proliferations; however, sometimes they can represent precancerous pathologies. The cytogenetic analysis of five mammary epithelial hyperplasias is reported. Four cases had clonal chromosome alterations. All of the cases presented a modal number of 46 chromosomes. Chromosome 9 monosomies and chromosome 1 deletions were common in these benign tumors. The study of benign proliferations of the breast may reveal a possible relationship between chromosomal alterations and the conditions of the tissue.