Title of article :
Deletion 5p11 accompanied by multiple numerical changes in testicular lymphoma
Author/Authors :
Espinoza، نويسنده , , Luis A. and Neto، نويسنده , , José Barbieri and Popescu، نويسنده , , Nicholas C. and Casartelli، نويسنده , , Cacilda، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
We describe a case of testicular B cell lymphoma with deletion of chromosome 5, del(5)(p11), as a sole structural abnormality. Histopathological diagnosis of the tumor was a high-grade lymphoma of the diffuse type containing cells positive for B cell specific antigen (CD20) and negative for the leukocyte common antigen (CD45). Deletion 5p may define the region of a tumor suppressor gene that could be associated with tumor progression and invasiveness and may serve as an indicator of poor prognosis in testicular lymphomas.
Journal title :
Cancer Genetics and Cytogenetics
Journal title :
Cancer Genetics and Cytogenetics