Author/Authors :
Molero، نويسنده , , Teresa and Lemes، نويسنده , , Angelina and de la Iglesia، نويسنده , , Silvia and Casares، نويسنده , , Ma Teresa Gَmez and del Mar Perera، نويسنده , , Ma Rosa Jiménez-Castellanos، نويسنده , , Santiago، نويسنده ,
Abstract :
Chronic lymphocytic leukemia (CLL) is rarely associated with secondary acute myelogenous leukemia (AML) usually due to chemotherapy or radiotherapy. No cases of concomitant CLL and acute promyelocytic leukemia (APL) have been found in the literature. Nevertheless, up to 12% of therapy-related AML cases are classified as APL. Of these latter, most are related to topoisomerase treatment, with a few acute cases occurring after radiotherapy. We report here a patient with an untreated CLL who developed APL 2 years after radiotherapy for prostate carcinoma.