Author/Authors :
Wu، نويسنده , , Dongdong and Gao، نويسنده , , Yanfeng and Qi، نويسنده , , Yuanming and Chen، نويسنده , , Lixiang and Ma، نويسنده , , Yuanfang and Li، نويسنده , , Yanzhang، نويسنده ,
Abstract :
Cancer is one of the leading causes of death worldwide. Conventional cancer therapies mainly focus on mass cell killing without high specificity and often cause severe side effects and toxicities. Peptides are a novel class of anticancer agents that could specifically target cancer cells with lower toxicity to normal tissues, which will offer new opportunities for cancer prevention and treatment. Anticancer peptides face several therapeutic challenges. In this review, we present the sources and mechanisms of anticancer peptides and further discuss modification strategies to improve the anticancer effects of bioactive peptides.
Keywords :
Cancer Therapy , Peptide , Modification strategy , Anticancer mechanism
