Title of article
Burkitt lymphoma following splenic marginal zone lymphoma: evidence for two independent B-cell clones
Author/Authors
Heintel، نويسنده , , Daniel and Streubel، نويسنده , , Berthold and Welzel، نويسنده , , Natascha and Le، نويسنده , , Trang and Schwarzinger، نويسنده , , Ilse and Haas، نويسنده , , Oskar A. and Simonitsch، نويسنده , , Ingrid and Lechner، نويسنده , , Klaus and Jaeger، نويسنده , , Ulrich، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
86
To page
88
Abstract
We report the progression of splenic marginal zone lymphoma (SMZL) with circulating villous lymphocytes to Burkitt lymphoma with the presence of a t(8;14)(q24;q32) followed by a highly aggressive course. While the initial indolent lymphoma had an IgM λ immunophenotype the Burkitt lymphoma was IgM κ-positive. Immunoglobulin heavy chain gene (IGH) sequence analysis showed no identity between the two clones. We conclude that Burkitt lymphoma can occur in patients with SMZL, although not necessarily of identical clonal origin.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
2003
Journal title
Cancer Genetics and Cytogenetics
Record number
1825143
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