Author/Authors :
Hong، نويسنده , , Bo and Chen، نويسنده , , Zhong and M Coffin، نويسنده , , Cheryl and Lemons، نويسنده , , Richard and Issa، نويسنده , , Bonnie and Brothman، نويسنده , , Arthur and Zhou، نويسنده , , Holly، نويسنده ,
Abstract :
We report a case of pleuropulmonary blastoma with complex cytogenetic abnormalities, including trisomy 2, trisomy 8, dup(7), der(10) t(8; 10)(q13; q22), add(17), and double minutes (dmin). Fluorescence in situ hybridization FISH analysis demonstrated TP53 deletion and amplification of MYCN; the latter has not been reported in PPB.
