Author/Authors :
Hishida، نويسنده , , Asahi and Matsuo، نويسنده , , Keitaro and Hamajima، نويسنده , , Nobuyuki and Ito، نويسنده , , Hidemi and Ogura، نويسنده , , Michinori and Kagami، نويسنده , , Yoshitoyo and Taji، نويسنده , , Hirofumi and Morishima، نويسنده , , Yasuo and Emi، نويسنده , , Nobuhiko and Tajima، نويسنده , , Kazuo، نويسنده ,
Abstract :
We conducted a hospital-based prevalent case-control study in a Japanese population (cases = 103, controls = 487) to ascertain the previous report about the association between the polymorphism in exon 13 of the hMSH2 gene (gIVS 12-6T→C) and the risk of non-Hodgkin lymphoma in an Ecuadorian population. When the TT genotype was defined as the reference, none of the CT genotypes (OR = 1.52; 95% CI, 0.97–2.37), CC genotypes (OR = 1.06, 95% CI, 0.44–2.54), or CT and CC genotypes combined together (OR = 1.44, 95% CI, 0.94–2.23) demonstrated significant OR. Further investigations with sufficiently larger populations and in other ethnicities are required to verify this association.
