Author/Authors :
Cavalli، نويسنده , , Luciane R. and Cornelio، نويسنده , , Deborah A. and Lima، نويسنده , , Rubens S. and Urban، نويسنده , , Cicero A. and Rone، نويسنده , , Janice D. and Cavalli، نويسنده , , Iglenir J. and Haddad، نويسنده , , Bassem R.، نويسنده ,
Abstract :
There are very few studies reporting DNA copy number changes in fibroadenomas of the breast. Using comparative genomic hybridization, we analyzed 20 paraffin-embedded samples of fibroadenomas of the breast from patients with no familial or previous history of breast cancer. No alterations in the DNA copy number were observed in any of the tumors analyzed, regardless of the chromosomal alterations observed using conventional cytogenetic analysis. We discuss our results and compare them to other reports on fibroadenomas.
