Author/Authors :
Fujieda، نويسنده , , Atsushi and Masuya، نويسنده , , Masahiro and Kitano، نويسنده , , Shigehisa and Miyazaki، نويسنده , , Kana and Yazaki، نويسنده , , Akira and Sugimoto، نويسنده , , Yuka and Usui، نويسنده , , Eiji and Miyata، نويسنده , , Eri and Shibasaki، نويسنده , , Tetsunori and Yamamura، نويسنده , , Kentaro and Ohishi، نويسنده , , Kohshi and Nishii، نويسنده , , Kazuhiro and Nakase، نويسنده , , Kazunori ، نويسنده ,
Abstract :
Deletion of the long arm of chromosome 15 is known as a rare but recurrent chromosomal abnormality in myeloid malignancies. We report a novel case of minimally differentiated hypoplastic acute myeloid leukemia (AML M0) in a patient who initially had a normal karyotype, but clonal interstitial deletion of chromosome 15, del(15)(q11.2q22), coincided with increment of leukemic cells a year later. We also summarize 18 published cases with myeloid malignancies and this chromosomal abnormality.
